Use of single nucleotide polymorphisms in the plcR gene for specific identification of Bacillus anthracis.

نویسندگان

  • W Ryan Easterday
  • Matthew N Van Ert
  • Tatum S Simonson
  • David M Wagner
  • Leo J Kenefic
  • Christopher J Allender
  • Paul Keim
چکیده

A TaqMan-minor groove binding assay designed around a nonsense mutation in the plcR gene was used to genotype Bacillus anthracis, B. cereus, and B. thuringiensis isolates. The assay differentiated B. anthracis from these genetic near-neighbors and determined that the nonsense mutation is ubiquitous across 89 globally and genetically diverse B. anthracis strains.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 43 4  شماره 

صفحات  -

تاریخ انتشار 2005